| Date |
Speaker
streaming video
|
Title of the 1o
Journal Paper |
Authors |
year,
journal |
volume:
pages |
food |
Jan 17
UCL
173 |
Cliff |
Scheduling
Building a Good Scientific Story
Full USD Syllabus for the Seminar course Serotonergic Psychedelics
|
CH Summers |
2020
|
|
|
Jan 31
UCL
173 |
Kevin
Krupp
|
Introduction to Serotonergic Psychedelics
Classic psychedelics as therapeutics for psychiatric disorders
Background paper:
MW Johnson 2018 International Review of Psychiatry 30: 285–290 Psychiatry might need some psychedelic therapy
|
CD Nichols
PS Hendricks
|
2020,
Handbook
Behavioral
Neurobiology
of Serotonin
2nd Edition Chapter 49 |
https://doi.org/:
10.1016/
B978-0-444-64125-0.00049-9 |
Jaz |
Feb 21
UCL
173 |
Kevin
Krupp
Cliff |
Fully automated head-twitch detection system for the study of 5-HT2A receptor pharmacology in vivo
Background papers:
Berthoux, Barre, Bockaert, Marin, Bécamel 2019 Cerebral Cortexdoi: 10.1093/cercor/bhy064: 1-11 Sustained activation of postsynaptic 5-HT2A receptors gates plasticity at prefrontal cortex synapses
Martin and Nichols 2016 EBioMedicine 11: 262–277 Psychedelics recruit multiple cellular types and produce complex transcriptional responses within the brain
How to chose a paper, What makes a good talk, Guide to Seminar Design
SN2ACKS Seminar Success Guide
Organization of your Talk
|
M de la Fuente
Revenga
JM Shin
HZ Vohra
KS Hideshima
M Schneck
JL Poklis
J González-Maeso |
2019
Scientific
Reports |
9:
14247:
1-14 |
Riley |
Feb 28
UCL
173 |
Ben
Onserio |
The hallucinogen 2,5-dimethoxy-4-iodoamphetamine hydrochloride activates neurotrophin receptors in a neuronal cell line and promotes neurites extension
Background papers:
Dakic et al., 2017 Scientific Reports 7: 12862: 1-13 Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT
Catlow, Jalloh, Sanchez-Ramos 2016 Neuropathology of Drug Addictions and Substance Misuse, Volume 2: 821–831 Hippocampal neurogenesis: Effects of psychedelic drugs. http://dx.doi.org/10.1016/B978-0-12-800212-4.00077
|
Z Marinova
S Walitza
E Gru¨nblatt |
2017
J Neural
Transm |
124:
749–759 |
Chinenye |
Mar 6
UCL
190 |
Avery
Del Grosso |
CaMello-XR enables visualization and optogenetic control of Gq/11 signals and receptor trafficking in GPCR-specific domains
Background papers:
Gao et al., 2018 Neuropharmacology 141: 167 – 180 Activation of 5-HT2A receptor disrupts rat maternal behavior
Gan, 2018 Brit J Anaesthesia 120: 818-826 5-Hydroxytryptamine 2A receptor inverse agonist pimavanserin impairs maternal behavior in postpartum female rats
|
H Zhou
Q Zhang
E Martinez
J Dale
S Hu
E Zhang
KLiu
D Huang
G Yang
Z Chen
J Wang |
2018
Nature
Communications |
9: 3751:
1–13
DOI: 10.1038/s41467-018-06295-x |
Ben |
Mar 27
UCL
173 |
Riley
Paulsen |
Chronic cannabis promotes pro-hallucinogenic signaling of 5-HT2A receptors through Akt/mTOR pathway
Background papers:
Viñals et al., 2015 PLoS Biology 13(7): e1002194. doi:10.1371/journal.pbio.1002194 1–40 Cognitive impairment induced by Delta9-tetrahydrocannabinol occurs through heteromers between cannabinoid CB1 and serotonin 5-HT2A receptors
De Gregorio et al., 2019 Pain 160: 136–150 Cannabidiol modulates serotonergic transmission
and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain
|
Ibarra-Lecue
I Mollinedo-Gajate
JJ Meana
LF Callado
R Diez-Alarcia
L Urigüen |
2018
Neuropsycho-
pharmacology |
5:
486-497 |
Naleeka |
Apr 3
UCL
173 |
Chinenye
Izuegbunam |
Psychedelics, but Not Ketamine, Produce Persistent antidepressant-like effects in a rodent experimental system for the study of depression
Background papers:
BD Sachs, JR Ni, MG Caron 2015 PNAS 112: 2557–2562 Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress
M Angoa-Perez, MJ Kane, DI Briggs, N Herrera-Mundo, CE Sykes,M Francescutti, DM Kuhn 2014 ACS Chemical Neuroscience 5: 908–919 Mice genetically depleted of brain serotonin do not display a depression-like behavioral phenotype
|
M Hibicke
AN Landry
HM Kramer
ZK Talman
CD Nichols |
2020
ACS
Chemical
Neuroscience |
11:
864-871 |
Jason |
Apr 17
UCL
173 |
Jaz
Yaeger |
Involvement of serotonin 2A receptor activation in modulating medial prefrontal cortex and amygdala neuronal activation during novelty-exposure
Background papers:
P Botta, A Fushiki, AM Vicente, LA Hammond, AC Mosberger, CR Gerfen, D Peterka, RM Costa 2019 PrePrint BioRxiv 1-47 An amygdala circuit mediates experience-dependent momentary exploratory arrests
E Hasegawa, T Maejima, T Yoshida, OA Masseck, S Herlitze, M Yoshioka, T Sakurai, M Mieda 2017 PNAS 114: E3526–E3535 Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity |
ME-S Hervig
NCH Jensen
NB Rasmussen
R Rydbirk
MV Olesen
Anders Hay-Schmidt
B Pakkenberg
S Aznar |
2017
Behavioral
Brain
Research |
326:
1–12 |
Avery |
Apr 24
UCL
173 |
Naleeka
Mohotti
Malwattage |
The endogenous hallucinogen and trace amine N,N-dimethyltryptamine(DMT) displays potent protective effects against hypoxia via Sigma-1 receptor activation in human primary iPSC-derived cortical neurons and microglia-like immune cells
Background papers:
Zhang 2017Neuropharmacology 116: 387e398 Sigma-1 receptor deficiency reduces GABAergic inhibition in the basolateral amygdala leading to LTD impairment and depressive-like behaviors
M Malik, C Rangel-Barajas, RH Mach, RR Luedtke 2016 Pharmacol Biochem Behav 218: 138–153 The effect of the sigma-1 receptor selective compound LS-1-137 on the DOI-induced head twitch response in mice
V Sabino, Cottone, SL Parylak, L Steardo, EP Zorrilla 2009 Behav Brain Res 198: 472–476 Sigma-1 receptor knockout mice display a depressive-like phenotype |
A Szabo
A Kovacs
J Riba
S Djurovic
E Rajnavolgyi
E Frecska |
2016
Frontiers in
Neuroscience |
10: 423
1–11 |
Zoom |
May 1
UCL
173 |
Jason
Gale |
A hallucinogenic serotonin-2A receptor agonist reduces visual response gain and alters temporal dynamics in mouse V1
Background papers:
Halberstadt, Chatha, Klein, Wallach, Brandt 2020 Neuropharmacology 167: 107933 1–12 Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species
Riga, Bortolozzi, Campa, Artigas, Celada 2016 Neuropharmacology 101: 370–378 The serotonergic hallucinogen 5-methoxy-N,N-dimethyltryptamine disrupts cortical activity in a regionally-selective manner via 5-HT1A and 5-HT2A receptors |
AM Michaiel
PRL Parker
CM Niell |
2019
Cell
Reports |
26:
3475–3483 |
Zoom |
|
|
Serotonergic Psychedelics Take Home Messages |
|
|
|
Summers
end